Our Evidence Architecture

Transparency about what's connected, what's AI-enhanced, and what's coming

Transparency Statement

TripSit.ai synthesizes insights using a combination of real API data (ClinicalTrials.gov, PubMed, FDA DailyMed) and AI-generated analysis. We are transparent about which sources are directly connected versus AI-enhanced. All insights should be validated before use in regulatory submissions or clinical decisions.

These sources have direct API integrations with real-time or cached data

API Connected
ClinicalTrials.gov
Real-time access to registered clinical trials from the official NIH database. We fetch Phase 3 and Phase 4 studies with enrollment data, sponsors, and study status.

Sources

ClinicalTrials.gov API v2

Update Frequency

Real-time with 24-hour cache

Limitations

  • Trial registration may lag actual study status
  • Limited to English-language trial records
API Connected
PubMed/NCBI
Real-time access to peer-reviewed medical literature via the NCBI E-utilities API. We fetch systematic reviews, meta-analyses, and clinical trial publications.

Sources

NCBI E-utilities APIPubMed Database

Update Frequency

Real-time with 24-hour cache

Limitations

  • Abstract-level data only; full text requires journal access
  • Citation counts not available via API
API Connected
Congress Abstracts
Curated abstracts from major medical society congresses. Data is manually loaded by our team from official conference proceedings.

Sources

EADVASCOAADESMOand more...

Update Frequency

Within 2 weeks of congress conclusion

Limitations

  • Coverage depends on manual curation effort
  • Not all congresses are currently loaded
API Connected
Global Regulatory Labels
Multi-region drug labeling data via the BioCore Regulatory Platform. Covers 8 regulatory authorities including FDA DailyMed (US), MHRA (UK), EMA (EU), Health Canada, SwissMedic, TGA (Australia), ANSM (France), and PMDA (Japan).

Sources

FDA DailyMed (US)MHRA (UK)EMA (EU)Health CanadaSwissMedic (CH)TGA (AU)ANSM (FR)PMDA (JP)

Update Frequency

Real-time with local database sync

Limitations

  • Label availability varies by region and product age
  • Some older labels may have limited structured data
API Connected
Biochemical Repositories
Molecular, chemical, and translational science data via the BioCore platform. Includes protein sequences, bioactive molecules, chemical classification, and drug interaction data from 7 specialized databases.

Sources

OpenFDA UNIINCATSUniProtChEMBLDrugCentralPubChemClassyFire

Update Frequency

Synced via BioCore platform updates

Limitations

  • Molecular data depth varies by compound novelty
  • Some newer biologics may have limited chemical classification
API Connected
Medical News RSS
Real-time aggregation of medical and pharmaceutical news from official RSS feeds including FDA, EMA, NIH, CDC, and PubMed Trending.

Sources

FDA Press ReleasesFDA Drug SafetyEMA NewsNIH NewsCDC NewsroomPubMed Trending

Update Frequency

Real-time

Limitations

  • Limited to sources with public RSS feeds
  • Article summaries only; full text requires visiting source
API Connected
Social & Patient Voice
Real patient discussions and sentiment from healthcare communities across Reddit, Twitter/X, YouTube, TikTok, LinkedIn, disease society sites, and manufacturer patient portals. For each drug/disease project, we also crawl disease-specific society sites (e.g., ADA, ACC, Obesity Society) and product patient portals (e.g., Wegovy.com, Keytruda.com) for condition-specific patient education, community discussions, and support resources.

Sources

Reddit APITwitter/X APIYouTube Data APITikTok Research APILinkedIn APIDisease Society SitesManufacturer Patient Portalsr/mediciner/pharmacyr/healthcarer/AskDocsr/ChronicPain

Update Frequency

Real-time with each insight generation; sentiment trends tracked historically

Limitations

  • Sentiment analysis uses keyword matching, not advanced NLP
  • Twitter/X and TikTok APIs may have rate limits
API Connected
FDA FAERS (Adverse Event Reporting)
Direct API integration with FDA's Adverse Event Reporting System (FAERS) via OpenFDA. Provides post-marketing safety surveillance data including adverse event frequencies, serious outcome rates, reporting trends, and top reported reactions for any drug.

Sources

FDA FAERS via OpenFDA APIPost-Marketing Safety ReportsMedWatch Voluntary Reports

Update Frequency

Real-time API queries; FAERS database updated quarterly by FDA

Limitations

  • Voluntary reporting system — does not capture all adverse events
  • Reports do not establish causation between drug and adverse event
API Connected
CMS HCAHPS Patient Experience
Direct API integration with CMS Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey data. Provides national patient experience benchmarks including communication quality, care transitions, medication communication, and overall satisfaction metrics.

Sources

CMS Provider Data APIHCAHPS National Survey ResultsHospital Compare Data

Update Frequency

Real-time API queries; CMS updates survey data annually

Limitations

  • National benchmarks — not drug-specific or therapy-area-specific
  • Survey data reflects hospital-level experience, not outpatient/specialty care
API Connected
Real-World Evidence Registries
Aggregated real-world evidence from post-marketing clinical trials, FDA safety databases, patient voice signals, and observational study publications. Combines Phase 4 trial data, post-marketing supplements, real-world patient experience reports, and published RWE studies to provide a comprehensive view of drug performance outside controlled trial settings.

Sources

ClinicalTrials.gov Phase 4 StudiesFDA Post-Marketing SupplementsBioCore Safety UpdatesPatient Voice SignalsPubMed Observational StudiesDisease Society ReportsFAERS Safety Reports

Update Frequency

Real-time with each insight generation; safety data synced daily

Limitations

  • RWE signals are aggregated from existing sources, not from direct claims or EHR databases
  • Patient-reported outcomes may not be representative of full patient population
Live Medical News Feed
Real-time updates from FDA, EMA, NIH, CDC, and PubMed

Connected RSS Feeds

FDA Press ReleasesFDA Drug SafetyEMA NewsNIH NewsCDC NewsroomPubMed Trending
How We Synthesize Evidence
Understanding the difference between API data and AI-generated content

API-Connected Data

When you see references to ClinicalTrials.gov, PubMed, or FDA DailyMed, these are fetched in real-time from official APIs. The NCT IDs, PMIDs, and drug label URLs are verified and link to actual records.

AI-Generated Analysis

Patient journey narratives, unmet needs analysis, strategic recommendations, and epidemiological context are generated by our AI model. While grounded in medical knowledge, these should be validated before use in formal settings.